Fioricet and Pregnancy
Fioricet is not recommended for pregnant or nursing women, as its components can affect a developing infant. Barbiturates have been shown to increase the risk of birth defects and brain tumors in the fetus. Caffeine in large doses may interfere with the baby's heart rhythm and growth.
If you become pregnant while taking this medication, inform your doctor immediately. If you are breastfeeding, your doctor will advise you to stop breastfeeding if you must take Fioricet. Fioricet and Children phentermine
Fioricet has not been tested for safety in children under 12 years old. Older children might be prescribed a reduced dose. Fioricet and Seniors
Fioricet may cause confusion, depression, or excitement in older adults. Your doctor will prescribe an individualized dose of Fioricet to minimize side effects.
Caffeine - As Fioricet contains caffeine, you should limit your intake of caffeine through coffee or over the counter stimulants such as Vivarin or NoDoz. Too much caffeine can cause rebound headaches and constipation as withdrawal symptoms.
Corticosteroids (cortisone) - Fioricet may make these medications less effective.
Corticotropin (ACTH) - Fioricet may make this medication less effective.
Desyrel (trazodone) - Risk of additive CNS depression.
MAO inhibitors - Fioricet must not be mixed with MAO (monoamine oxidase) inhibitors such as the antidepressants Nardil, Marplan, or Parnate.
Narcotic pain medication, like Codeine, Demerol (meperidine), Buprenex (buprenorphine), Darvon (propoxyphene), Dilaudid (hydromorphone), MS Contin or Kadian (morphine), nalbuphine, OxyContin (oxycodone), Percocet (oxycodone, acetaminophen), Stadol (butorphanol), Talwin compound (pentazocine), Vicodin (hydrocodone, acetaminophen), or Vicoprofen (hydrocodone, ibuprofen) should not be mixed with Fioricet.
Norflex (orphenadrine) - Risk of oversedation.
Oral contraceptives - Butalbital may make these medications less effective.
Sedatives like Fiorinal, Phenobarbitol, Seconal, or barbiturates of any other kind, should not be mixed with butalbital.
Sleep medication like Ambien (zolpidem), Sonata (zaleplon), or over the counter sleeping pills should be used with butalbital only as, and if, advised by your doctor.
Skeletal muscle relaxants - such as Flexeril (cyclobenzaprine), Skelaxin (metaxalone), Soma (carisoprodol), or Robaxin (methocarbamol) should not be mixed with Fioricet.
Street drugs, such as barbiturates or opiates, must never be mixed with Fioricet as this could result in a fatal overdose.
Tegretol (carbamazepine)
Tranquilizers such as Haldol (haloperidol), Mellaril (thioridazine), or Thorazine (chlorpromazine) may cause oversedation; they should not be mixed with butalbital.
Tricyclic antidepressants such as Elavil (amitriptyline), Asendin (amoxapine), Anafranil (clomipramine), Pertofrane or Norpramin (desipramine), Sinequan (doxepin), Tofranil (imipramine), Aventyl or Pamelor (nortriptyline), Vivactil (protriptyline), and Surmontil (trimipramine), may increase the central nervous system suppressant effects from either the antidepressant, or the Fioricet.
Valproic acid, also Depakote, Depakene, divalproex.
Wellbutrin/Zyban (bupropion) - Barbiturates such as butalbital may decrease levels of bupropion in the body.